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ERITROCITOSIS PATOLÓGICA DE ALTURA: Caracterización biológica, diagnóstico y tratamiento. HIGH ALTITUDE PATHOLOGICAL ERYTHROCYTOSIS. Diagnóstico y tratamiento | 23 DIC Eritrocitosis. Actualización de los métodos diagnósticos y el manejo de los pacientes con eritrocitosis. 3. original research. DOI: Secondary erythrocytosis due to hypoxemia as prognosis. in exacerbated chronic .

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Multivariate analysis of prognostic factors for the composite outcome. Hemorheology in the erythrocytoses.


Patients with congenital heart disease, for whom diagnosis of exacerbation of lung disease editrocitosis discarded at discharge, and those who did not wish to participate in the study were excluded from the study. Hematocrit and the risk of cardiovascular disease—the Framingham study: Universidad Nacional de Colombia.

This research could not determine any relationship between egitrocitosis parameters and prognosis of patients suffering from pulmonary diseases; nevertheless, extreme values of hematocrits tended to have adverse outcomes. Paraclinical variables at admission.

Efficacy and safety of low-dose aspirin in polycythemia vera.

Eritrocitosi the minority of patients had a severe functional class IVthe use of long-acting bronchodilators was limited to only five cases, compared with the more eritrocitoosis use of methylxanthines. The qualitative variables were reported as absolute and relative frequencies. Type chronic lung disease. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera.

To establish the association between the independent qualitative variables and the dependent or outcome variable, the Chi square test of independence X 2 was used along with the Mantel-Haenszel method.

None of these patients presented any of the outcomes assessed at 30 days. Since the NYHA functional class and the use of medications did not differ due to hematocrit levels, erythrocyte parameters in this cohort did not appear to have any relation to the severity of chronic lung disease in patients.

Vascular and neoplastic risk in a large cohort of patients with polycythemia vera. Acute exacerbations of chronic obstructive pulmonary disease.

Thus, determining the implications of erythrocyte parameters might contribute to define the usefulness of phlebotomy or red blood cells transfusion in these patients. There was no difference between sexes regarding the type of prescription medications.


The most frequently used medications were short-acting bronchodilators, and their combination was the most common association, followed by association with inhaled steroids. Other outcomes did not appear to have any relation to hematocrit levels, although no deaths were recorded in the group of patients with the highest levels of hematocrit. The definition of chronic lung disease that was coined sought to be sensible, considering that few patients have pulmonary physiology studies and that some of those who actually had them were not available at the time of the survey or follow-up.

Effects on pulmonary hemodynamics, gas exchange, and exercise capacity. Patients over 18 years of age, with a history of chronic lung disease, hypoxemia at admission and diagnostic impression of exacerbation of, infectious or non-infectious, chronic lung disease were selected.

Funding None stated by the authors.

Repetitive hemodilution in chronic obstructive pulmonary disease and pulmonary hypertension: Regarding red blood cell parameters, a tendency to have a protective effect when located in the core values of hematocrit against extreme values, this difference did not show a statistical significance.

Domiciliary oxygen for chronic obstructive pulmonary disease. Epidemiology of myeloproliferative neoplasms in the United States. In long-term observations, anemia has been identified as a factor involved in the development of adverse events in patients with stable chronic lung disease, whereas erythrocytosis has shown its inference on a better prognosis Follow-up was completed for Patients. Another limitation of the study was establishing definitions accepted for inclusion criteria and data analysis.

Revista de la Facultad de Medicina

Variables were described using an additional categorization by hematocrit levels and an adjustment in a multivariate model through logistic regression.

The results suggest the eritrocitosiz for further studies to clarify the relevance of erythrocyte parameters in exacerbations of chronic lung disease, both at sea level and in populations located at higher altitudes, as in this case. On the other eritrocitossi, the presence of the exacerbation did not differ according to the Trataimento criteria, but did show a trend to greater affectation of oxygenation and hypercapnia in the presence of higher hematocrit levels.


Depending on the outcome, the abnormally distributed variables were reported by their median and interquartile range, while those presenting normal distribution were reported by their mean and standard deviation. Demographic, clinical and paraclinical variables supported in the literature were included. Type of chronic lung disease.

Symptomatic and puomonary response to acute phlebotomy in secondary polycythemia. At each step, the fulfillment of the criteria for inclusion and exclusion was verified.

Am J Hematol ; Chronic obstructive pulmonary disease. Regarding the outcomes, there was a predilection to higher length hospital stay in the presence of lower levels of hematocrit.

Br J Haematol ; No relationship between a history of use of home oxygen and hematocrit values was found. This study attempted to establish the relationship between red blood cell parameters and the development of adverse outcomes at 30 days in patients with exacerbated chronic lung disease. In-hospital mortality following acute exacerbations of chronic obstructive pulmonary disease.

Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: Determining which patients had chronic hypoxemia at admission was difficult because, in most cases, there were no data, and for those who received home oxygen its indication was unknown. Bivariate analysis of prognostic factors for the composite outcome.

Am J Med ; Introduction Chronic lung diseases are common and their exacerbations are the main cause of consultation in the emergency department since they impair the quality of life of patients The variables in the bivariate analysis that were statistically significant to be included in the multivariate analysis were age, history of hypertension, history of heart failure, use of short-acting anticholinergics, home oxygen, type of Anthonisen and hematocrits at admission, being blood pressure the factor with the greatest weight Table 3.

Complications during hospital stay.